After graduating, Qureshi started his own business. He also became involved in politics and was elected to the National Assembly of Pakistan in 1990. He has held various government positions, including Minister of Finance, Minister of Commerce, and Minister of Foreign Affairs.
Qureshi is also a practicing astrologer and has written several books on astrology. He is considered one of the most respected astrologers in the world and is often consulted by politicians and celebrities.
In addition to his work as an astrologer, Qureshi is also a philanthropist and has donated millions of dollars to various charitable causes. He is the founder of the Ghulam Sarwar Qureshi Foundation, which provides scholarships to underprivileged students and supports various other social welfare projects.